THE FOUNDING COLLECTION · COMING SOON
DEMERE® · OUR FORMULATION PHILOSOPHY

The ingredient.
The delivery. The detail.

A closer look at CBG, the skin barrier and the formulation decisions behind DeMere.

01

THE INGREDIENT

CANNABIGEROL

The mother cannabinoid.

A name rooted in the plant.
A new perspective on skin care.

Cannabigerol, or CBG, is a non-intoxicating cannabinoid. Its nickname comes from the role of cannabigerolic acid, CBGA, in the plant: CBGA is a starting point for several other cannabinoids, including the precursors of CBD and THC. CBG itself forms from CBGA.

DeMere’s interest is in CBG’s own properties. Our planned formulas pair hemp-derived CBG with nano-liposomal encapsulation for a daily cosmetic skincare ritual.

Explore the cannabinoid research ↗
A DELIBERATE CHOICE

Why CBG,
not CBD.

Different molecules. Different areas of interest. DeMere chose CBG for its distinct activity profile and the emerging research around its role in topical skin care.

THE DEMERE FOCUS

CBG

Cannabigerol

Non-intoxicating, with published research exploring antioxidant activity and skin responses to irritation.

A DIFFERENT CANNABINOID

CBD

Cannabidiol

Also non-intoxicating, with its own biological activity and research history. CBG and CBD are distinct ingredients.

What drew our attention

Oxidative stress
Laboratory studies have explored CBG’s antioxidant activity.
Skin comfort
Research has examined inflammatory signals and the response of experimentally irritated skin.
A distinct profile
CBG and CBD have shown different activity in selected laboratory tests, giving formulators a reason to consider each on its own merits.

One published evaluation combined laboratory testing with a small, 20-participant study of a 0.1% CBG serum on experimentally irritated skin. These early findings help explain our interest in the ingredient. Read the published CBG study ↗

02 / THE DELIVERY

The skin barrier.
The delivery approach.

The stratum corneum is the skin’s outermost layer: cells surrounded by lipids that help retain moisture and regulate what passes through. Understanding that barrier is part of designing a topical formula.

Skin-barrier diagram showing a phospholipid carrier at the surface, interaction and release in the stratum corneum, and released ingredients within the skin.
Lipid carriers meet the skin’s outer layers, where they can deposit ingredients and influence their release.Scroll sideways to explore the diagram.
I

Encapsulate

Liposomes are microscopic lipid vesicles that can hold ingredients within a formulation.

II

Protect

DeMere’s formulation approach is designed to help protect CBG inside the cream through encapsulation.

III

Release

The carrier is part of how an ingredient is presented to the skin. DeMere’s approach is designed with release over time in mind.

Read about liposomes and the skin barrier ↗
03

THE PROCESS

FORMULATED WITH INTENTION

Assembled cold,
by design.

The development approach includes cold-process emulsification, chosen to limit heat exposure during formulation. Ingredient selection, encapsulation and process design are considered together.

The aim is a complete formulation: CBG, its lipid carrier and the cream that brings them into your daily routine.

Explore the twice-daily ritual
THE FOUNDING COLLECTION

The beginning of
something considered.

Four rituals. One new perspective on skin care.
Discover what is taking shape at DeMere.

Explore the launch