EXPLORE THE FOUNDING COLLECTION
DEMERE® · OUR FORMULATION PHILOSOPHY

The ingredient.
The delivery. The detail.

A closer look at CBG, the skin barrier and the formulation decisions behind DeMere.

01

THE INGREDIENT

CANNABIGEROL

The mother cannabinoid.

A name rooted in the plant.
A new perspective on skin care.

Cannabigerol, or CBG, is a non-intoxicating cannabinoid. Its nickname comes from the role of cannabigerolic acid, CBGA, in the plant: CBGA is a starting point for several other cannabinoids, including the precursors of CBD and THC. CBG itself forms from CBGA.

DeMere’s interest is in CBG’s own properties. Our facial and body repair formulas pair hemp-derived CBG with proprietary Multi-Environment nano-liposomal encapsulation for a daily skincare ritual.

Explore the cannabinoid research ↗
A DELIBERATE CHOICE

Why CBG,
not CBD.

Different molecules. Different areas of interest. DeMere chose CBG for Facial Repair and Body Repair for its distinct activity profile and the emerging research around its role in topical skin care. Sleep Care and Stress Relief use CBD for their sleep and stress-relief focus.

FACIAL & BODY REPAIR

CBG

Cannabigerol

Non-intoxicating, with published research exploring antioxidant activity and skin responses to irritation.

SLEEP CARE & STRESS RELIEF

CBD

Cannabidiol

Also non-intoxicating, with its own biological activity and research history. DeMere uses CBD in its sleep and stress-relief formulations.

What drew our attention

Oxidative stress
Laboratory studies have explored CBG’s antioxidant activity.
Skin comfort
Research has examined inflammatory signals and the response of experimentally irritated skin.
A distinct profile
CBG and CBD have shown different activity in selected laboratory tests, giving formulators a reason to consider each on its own merits.

One published evaluation combined laboratory testing with a small, 20-participant study of a 0.1% CBG serum on experimentally irritated skin. These early findings help explain our interest in the ingredient. Read the published CBG study ↗

02 / THE DELIVERY

The skin barrier.
The delivery approach.

The stratum corneum is the skin’s outermost layer: cells surrounded by lipids that help retain moisture and regulate what passes through. Understanding that barrier is part of designing a topical formula.

Skin-barrier diagram showing a phospholipid carrier at the surface, interaction and release in the stratum corneum, and released ingredients within the skin.
Lipid carriers meet the skin’s outer layers, where they can deposit ingredients and influence their release.Scroll sideways to explore the diagram.
I

Encapsulate

Liposomes are microscopic lipid vesicles that can hold ingredients within a formulation. Nano-liposomes are much smaller vesicles that can penetrate and distribute active ingredients such as CBG in a much more efficient and uniform manner. DeMere’s proprietary Multi-Environment nano-vesicles are multilamellar, meaning that they can store the different ingredients in different layers of the vesicle, which allows for a more precise and complex delivery of the synergistic active ingredients.

II

Protect

DeMere’s proprietary formulation approach is designed to help protect CBG and other ingredients inside the cream through encapsulation so that when they are released, they maintain their effectiveness.

III

Release

This is the magic of DeMere’s proprietary Multi-Environment nano-liposomal delivery system. This carrier system allows the active ingredients to be delivered to different depths of the skin and at different time points. This results in a more effective change and for an extended period of time.

Read about liposomes and the skin barrier ↗
03

THE PROCESS

FORMULATED WITH INTENTION

Assembled cold,
by design.

Cold-process emulsification protects the active ingredients since heat emulsification can destroy them. Cold emulsion for the DeMere collection adds to its lightweight feel and allows the cream to absorb more efficiently. In addition, cold emulsification uses less energy and is better for the environment. Ingredient selection, encapsulation and process design are considered together.

A complete formulation brings together CBG, its lipid carrier and the environmentally sound cream that brings them into your daily routine.

Explore the twice-daily ritual
THE FOUNDING COLLECTION

The beginning of
transformation considered.

Four rituals. One new perspective on skin care.

Discover the collection